Showing posts with label breast cancer. Show all posts
Showing posts with label breast cancer. Show all posts

Thursday, July 12, 2018

"My interruption": One woman's diagnosis with cancer

Marie Sutton
Marie Sutton is a strategic communications professional, author, wife and mother of two. She was diagnosed with HER2 positive breast cancer in January 2018. This post originally appeared on her blog and is reprinted here with her permission.

The Birmingham sky was postcard pretty on the Friday that I found out I have Stage 3 breast cancer. Brilliant brushstrokes of cerulean stretched from East Lake to West End and the sun pierced through the sky. It was like the setting of a dream, but the snap of cold in the air reminded me that it wasn’t.

It was lunchtime, and my team and I were interviewing for an opening in our department. The candidate, a woman, was in her early thirties. She had a messy ponytail, cheap mail-order tortoiseshell glasses and wore an ink blue pants suit that revealed her skinny legs. Five minutes into her talk, I wrote the words: “She’s a no.” She rambled and complained about her former employer and my mind drifted toward lunch.

I discreetly pulled out my phone underneath the table and scrolled through emails while she answered the questions from our prepared list. I saw that I had missed a call from an “801” number and my heart began to beat in my chest.

I clumsily excused myself from the room, walked over to a corner of the hallway and dialed my voicemail. The woman's message began with a sigh, and then, in a heavy African accent, said, “Mrs. Sutton, I have your results. Please call me.”

My knees began to buckle and I looked around for a place to go. I walked out onto the student center patio and tried to steady my fingers while calling back the number.

“Are you somewhere where you can talk?” the doctor said.

“Yes,” I said.

“Do you want me to call you back when you can talk?”

“No,” I said. My stomach was in knots and I felt I as if was going to throw up.

“Well...I am the doctor who did your biopsies. Do you remember me?”

“Yes,” I said, becoming annoyed. It had been less than 48 hours since she was pulling tissue from my right breast and lymph nodes. How could I forget?

“Well, we tested all three of the areas and all three came back cancer.”

Her words felt like a sledgehammer to the side of my head. Vibrations were coming from my skull and her words seeped in, in slow motion.  

With each word she spoke – “metastasized” and “mastectomy” – a part of me slowly deflated. I thought of my 10-year-old daughter who loves art and hangs on my every word and of my 9-year-old baby boy who wants to save all the animals and enjoys kissing my cheeks. I thought of the possibility of dying. I was just two weeks shy of my 44th birthday. 

After I hung up, her words were still sitting in my ear. I tried to get them out with my finger, but they were stuck.

I sat and stared for a moment. I spotted a man in the distance on the fifth floor of a parking deck. He was near the edge of the guardrail. “What is he doing,” I thought to myself. Was he going to jump?

Maybe I should jump.

I called my husband and without taking a breath, blurted out, “They said I have cancer.”

“I’m on my way,” he said and immediately came to my job. I walked toward the parking lot in a daze. I left my purse, my car, my keys, my coat. 

When I got into his gray Infiniti, he grabbed my hand and said, "I'm sorry."

I didn’t speak, couldn’t speak.
He held my hand the entire drive. I stared out the window and tried to find words to say.
When we got home, he and I prayed, ate sandwiches, and watched episodes of “Comedians in Cars Getting Coffee.” We didn't know what else to do, so we laughed and cried and braced ourselves for cancer.

Follow more of Marie’s story through diagnosis and treatment on her blog marieasutton.com. 

Wednesday, May 16, 2018

The Role of Exercise During and After Cancer Care


Exercise plays a crucial role in healthy living during and after cancer treatment. However, cancer patients and survivors may need to exercise less intensely and complete their workout at a slower pace than they are used to.

Exercise doesn’t need to be strenuous in order to produce results. “Research has shown that exercise is not only safe and possible during cancer treatment, it can actually improve how well you function physically and how well you feel ,” says Teri Hoenemeyer, Ph.D., director of Education and Supportive Services at the UAB Comprehensive Cancer Center.”Adding more physical activity to your daily routines can include: walking around your neighborhood after dinner, doing yard work, house cleaning, using the stairs or parking farther away from a building than usual or taking 10-minute walking breaks during the day.

“Fatigue during and after chemotherapy and radiation can make you want to limit your physical activity too much, but completely stopping can actually increase fatigue, creating a vicious cycle,” Hoenemeyer says. “In fact, recent studies indicate that exercise that increases your heart rate, like fast walking, can reduce fatigue.”

In addition to physical benefits, there are many mental benefits of exercise. Exercise can help you relax, and it relieves anxiety. It also reduces your chances of developing anxiety and depression.

“Having an outlet, like exercise, to relieve stress is an important part of getting well and staying healthy,” Hoenemeyer adds. Other benefits of exercise during cancer treatment include:
Improved balance, decreased risk of falls and broken bones
  • Maintained muscle tone 
  • Decreased risk of heart disease 
  • Decreased risk of osteoporosis (weak bones that are more likely to break) 
  • Improved blood flow to legs and decreased risk of blood clots 
  • Improved self-esteem 

Even though there is still a lot of research on the effects of exercise on cancer recovery and on the immune system that needs to be done, most agree that regular exercise during and after a cancer diagnosis has positive health benefits. Physical activity may also reduce the risk of getting the following types of cancer or prevent cancer from recurring:
  • Breast cancer 
  • Colon cancer 
  • Endometrial cancer 
  • Advanced prostate cancer 
  • Pancreatic cancer 

Exercise and increased physical activity can also help prevent chronic conditions like heart disease, diabetes, osteoporosis and hypertension.

When starting an exercise program or routine, each person will have different physical abilities due to their age, diagnosis and prior exercise experience so it is important to talk to your doctor before starting. Here are a few tips for starting an exercise routine:
  • Start slowly and take frequent breaks 
  • Use a mix of muscle groups for strength training, aerobics, and flexibility 
  • Always warm up first and stretch afterward 
  • Don’t push yourself and listen to your body 
  • Take deep breaths and relax! 

For more information on current exercise recommendations for cancer patients and survivors, visit the American Cancer Society online.

Take the first step in starting an exercise route by joining us on Saturday, June 2 for the UAB Comprehensive Cancer Center’s inaugural Lace Up for a Cure, a 2K (1.3 mile) walk raising awareness and education of services offered at the UAB Cancer Center and bringing together individuals who have been touched by cancer.

All ages are welcome. Free onsite parking is available. Learn more and register today!















Monday, October 16, 2017

Breast Cancer—Early Detection and Screening

October is breast cancer awareness month but women need to be aware of breast health all year long.

“Despite the magnificent strides in breast cancer research, women still need to adhere to screening guidelines recommended for their age group, especially if they have
a family history of breast cancer,” says Catherine Parker, M.D., a fellowship trained breast cancer surgeon at the University of Alabama at Birmingham.

According to the American Cancer Society, there will be 252,710 new cases of invasive breast cancer among U.S. women in 2017. And finding breast cancer early is one of the most important strategies to prevent death from the disease. When breast cancer is found early, it is small and has not spread, making it easier to treat successfully.

“The good news is that we’re living in a time when women are surviving the disease. In fact, the population of survivors is expected to grow,” says Parker. “However, we still need to be vigilant and take measures to protect ourselves.”

The ACS recommends that women who are at average risk for breast cancer start getting mammograms yearly at age 45 but have the choice to start having annual mammograms at age 40. Women 55 and older should switch to mammograms every 2 years, or continue yearly screening.

“Mammograms do not detect every breast cancer. Women at every age should be familiar with how their breasts normally look and feel, as well as be familiar with signs and symptoms of breast cancer,” says Parker. Although there are differing opinions about the benefits of self-breast exams, it is important for patients to know the proper technique, what to look for, and what is their normal; for example, has one breast always been smaller or has one nipple always turned inward; therefore, self-breast awareness should begin in late teens and early 20’s.

The most common symptom of breast cancer is a new lump or mass in the breast. A painless, hard mass that has uneven edges is more likely to be cancer, but breast cancers can be tender, soft, or rounded. For this reason, it is important to have any new breast mass, lump, or change in breast checked by a health care professional.

Other possible symptoms of breast cancer include:
• Swelling of all or part of a breast (even if no distinct lump is felt)
• Skin irritation or dimpling of the skin
• Breast or nipple pain
• Nipple retraction (turning inward)
• Redness, scaliness, or thickening of the nipple or breast skin
• Nipple discharge (other than breast milk)

For women who have a family history of breast cancer, the UAB Breast Health Center offers comprehensive guidance on risk assessment, genetic testing, screenings, and prevention strategies. Furthermore, the Center takes a multidisciplinary approach to cancer care. When patients are diagnosed with breast cancer they are immediately assigned a team of specially trained breast cancer experts (a medical oncologist, radiologist and surgeon) who are able to give them individualized recommendations regarding their diagnosis, treatment, surgery, and recovery. The clinic is also able to offer first and second opinions for any problems related to the breast.

“The program is also able to offer screening and clinical management for women who have an increased risk of both ovarian cancer and breast cancer,” says Parker.


For more information about early detection and screening, click here.




Wednesday, July 23, 2014

Why Give Wednesday: Breast Cancer

What is Breast Cancer?
Breast cancer is a malignant (cancer) tumor that starts in the cells of the breast. It occurs in both men and women, although male breast cancer is rare. It is estimated that there will be 232,570 new cases of invasive breast cancer in women this year and about 40,000 women will not survive. Breast cancer is the most common cancer among women in the United States, other than skin cancer. It is the second leading cause of cancer death in women, after lung cancer.

What is UAB doing to find the cure?
The UAB Comprehensive Cancer Center is a nationally recognized leader in the field of breast cancer research. The center is one of only 11 institutions in the nation to hold a SPORE (Specialized Program of Research Excellence) grant in breast cancer. These highly prestigious grants are designed to move research findings quickly and safely from the laboratory to the clinical setting.
Komen Promise Grant awardees at UAB
The Cancer Center is also a member of the Translational Breast Cancer Research Consortium, a national group of 14 research centers that conducts innovative, high-impact clinical trials in breast cancer. Also, in 2009, the Cancer Center was awarded a $6.4-million Promise grant from the Susan G. Komen Foundation to study triple-negative breast cancer, a particularly aggressive form of the disease.

Breast Cancer Research Foundation of Alabama
Since 1996, the BCRFA has raised and invested nearly $4 million dollars of seed money to pave the way for the UAB Comprehensive Cancer Center to receive sought-after and sustaining grant dollars. These funds have been instrumental in developing the following:
-$11.5 Million Dollar Grant Pilot funding that led to the receipt and renewal of the Breast Cancer SPORE Grant (Specialized Program of Research Excellence)
-Microarray Facility Helped create the UAB CCC Microarray Facility that can determine the genetic footprint of breast cancers
-$6.4 Million Dollar Grant Pre-clinical lab testing to prepare for a $6.4 million Promise Grant from the Komen Foundation to change the prognosis and treatment of Triple Negative Breast Cancer
-Imaging Facility Helped fund the In Vivo Imaging facility which supports Three Distinct Research Studies in breast cancer
-Talent Funds to recruit and retain world-class breast cancer researchers


Dr. Edward Partridge, UAB CCC director
“The BCRFA works tirelessly to raise money for breast cancer research at the UAB Comprehensive Cancer Center.  Their investment provides essential pilot funding for several projects that have potential to translate into new discoveries for cures and disease modifying treatments. This philanthropic support is absolutely critical, enabling us to receive additional, high-profile grants, as well as recruit and retain world-renowned breast-cancer researchers. For every dollar we receive from charitable contributions, the UAB Comprehensive Cancer Center is able to generate an average of $16 in federal and other funding.” - Dr. Edward Partridge, UAB Comprehensive Cancer Center Director

The Breast Health Center at UAB
The UAB Breast Health Center is a leader in breast cancer diagnosis, treatment and research. With a multi-team approach to caring for patients battling breast cancer, the UAB Breast Health Center provides state-of-the-art treatment options and follow-up care. The Breast Health Center has a team of physicians with a strong passion for breast cancer and the patients it touches. Because our physicians are nationally recognized breast cancer specialists in oncology, hematology, surgical oncology, and radiation oncology, you can rest assured you’re receiving the best care available. We work with specialists in other areas of care when necessary to give you a comprehensive approach to treatment.



Why Choose UAB?
The Breast Health Center at UAB is unique in that we offer comprehensive breast health services that include screening, risk assessment, prevention strategies, diagnosis, treatment, rehabilitation, and research. The UAB Breast Health Center has earned full accreditation by the National Accreditation Program for Breast Centers (NAPBC), a group of professional organizations from around the country dedicated to improving the quality of care and the monitoring of outcomes for patients with diseases of the breast. You can reach the UAB Breast Health Center at 205.801.8266.


Visit our website for more information, your support is greatly appreciated. Donations are accepted here. 

Thursday, March 13, 2014

BCRFA Presents Annual Donation

BCRFA Co-Founders Bruce Sokol and Dolly O'Neal,
2014 Honoree Jean Thompson and
CCC Director Dr. Ed Partridge
Last week, I had the pleasure of accepting, on behalf of the UAB Comprehensive Cancer Center, this year's donation from one of the Cancer Center's most loyal and longstanding community partners, the Breast Cancer Research Foundation of Alabama. 

The BCRFA hosts events and other fundraising opportunities throughout the year, and in turn donates all of its proceeds to the Cancer Center for breast cancer research. This year these dedicated volunteers presented us with a check for $500,000!

The Cancer Center hosted a special luncheon for the BCRFA and several of its supporters, which gave us the opportunity to present updates on the research being funded by their donation. Dr. Andres Forero, one of our leading breast cancer specialists, explained several promising research projects that could potentially change the way some breast cancers are treated. Many of those projects involve drugs and therapeutic agents developed here at UAB, using the very money provided by the BCRFA.   

What began as a small grassroots effort with just a few people has turned into an amazing organization that, to date, has raised more than $4.5 million for breast cancer research at the UAB Comprehensive Cancer Center. That support has helped turn the Cancer Center's breast cancer research and clinical enterprise into one of the premier programs in the United States.

The support of the Breast Cancer Research Foundation of Alabama is critical to our success here at the Cancer Center, and I am proud to have them as a community partner. I again want to thank the BCRFA board and staff for all of their hard work in taking the organization forward. They truly set the standard for a group who wants to make a difference in the fight against cancer. The Cancer Center and I thank them for their support.

-Ed Partridge, M.D.

Friday, July 13, 2012

SPORE grants set UAB apart

The UAB Comprehensive Cancer Center is one of few institutions to have been awarded three or more SPORE (Specialized Program of Research Excellence) grants from the National Cancer Institute. Currently the center holds SPORES in pancreatic and breast cancer and is partnered with John Hopkins University on a cervical cancer SPORE. Additionally, the Cancer Center was the only institution nationwide to receive a SPORE grant in pancreatic cancer in 2010. Why is this grant such a big deal?

It supports projects that will lead to the early detection, prevention, diagnosis and treatment of human cancers. Each SPORE is focused on a specific organ site, such as breast or pancreatic cancer. "SPOREs are designed to enable the rapid and efficient movement of basic scientific findings into clinical settings, as well as to determine the biological basis for observations made in individuals with cancer or in populations at risk for cancer," according to the National Cancer Institute.

Principal investigator Donald J. Buchsbaum, Ph.D., director of radiation biology at the University of Alabama at Birmingham, leads the SPORE program in pancreatic cancer. Support from the NCI was granted because of the Cancer Center's expertise in tumor biology, virology/gene therapy, immunobiology and targeted immunotherapy. Current research projects stem from previously established efforts that showed the most promise.

Kirby I. Bland, M.D., chair of the department of surgery at the University of Alabama at Birmingham, is the principal investigator of the SPORE program in breast cancer. In order to best accomplish the goal of prevention, detection, prognosis and therapy development, this project assembled many basic and clinical scientists, including molecular/cell biologists, pathologists, medical/surgical oncologists, experts in the development of new technologies, and biostatisticians.

There are currently 62 grants across 23 states in the country. UAB claims Alabama's only SPORE grants. Just another example of what sets the UAB Comprehensive Cancer Center apart.

-Ed Partridge, M.D.

Monday, October 24, 2011

Too Much Pink? Or Not Enough?

As Breast Cancer Awareness Month comes to a close, it's been incredibly rewarding to see the sheer number of pink events that have occurred across our community this year. It seems that October gets "pinker" every year, which I think is a very great thing.

But for some, the question has arisen: Is there too much pink, and is it glamorizing breast cancer? To answer the first part of that question, I say no. The amount of awareness generated by pink events is tremendous, and even more importantly, the amount of research dollars raised has allowed us to make significant advancements in the understanding and treatment of the disease. As I've said many times before, research is the foundation for eliminating cancer, and without it, all cancers - including breast cancer - would be a death sentence, like they were just a few decades ago.

As for whether breast cancer is becoming glamorous, it is important to remember the realities of this disease. According to the National Cancer Institute, more than 230,000 new cases of breast cancer will be diagnosed in 2011, and more than 39,000 deaths will occur because of it. And while the overall five-year survival rate is around 89 percent, it is still the second-leading cause of cancer death among women (after lung cancer).

I do, however, encourage you to do your research to make sure your donations go to the right cause or organization, such as the American Cancer Society, Susan G. Komen for the Cure, or us at the UAB Comprehensive Cancer Center, where 100 percent of your donation will go directly toward research.

So, is there too much pink? No, there isn't. But we need more colors! For instance, November is both lung cancer and pancreatic cancer awareness month. Wouldn't it be great to see Birmingham covered in pearl for lung cancer and purple for pancreatic cancer? Or in teal for Ovarian Cancer Awareness Month in September? Or dark blue for March's Colorectal Cancer Awareness Month? We should not, and must not, limit cancer awareness for one month out of the year.

Cancer is a 24-7-365 fight, and we need to be all in this together. I thank you for your support!

-Ed Partridge, M.D.

Wednesday, October 5, 2011

Big News During a Busy Month

October has gotten off to an extremely busy start here at the UAB Comprehensive Cancer Center! We began the month by announcing the renewal of our National Cancer Institute (NCI) designation as a "comprehensive" cancer center - a status that we have maintained for 40 years.

Our NCI designation is what sets us apart in our state and region. We are the only comprehensive cancer center in Alabama, and the only one in the Deep South area that stretches from South Carolina to Louisiana and Arkansas. To maintain this designation, we must undergo a rigorous and extensive review process every five years in which members of our peer institutions across the country travel to our center to examine every aspect of our research enterprise.

During our most recent review, we received an excellent rating, with special emphasis placed on our community outreach and population-based studies and our translational research (moving scientific findings from the laboratory setting to the patient bedside). Our renewed grant is $27.5-million for the next five years, which allows us to maintain and grow our infrastructure that allows our scientists to conduct the cutting-edge research that we are known for.

On Monday,  to kick off Breast Cancer Awareness Month, the Birmingham News "turned pink" for the second year in an effort to increase cancer awareness. This year, the paper extended its coverage to all cancers, and not just breast cancer. I was especially pleased to see that our Cancer Center was featured prominently in several stories.

Of course, with this being Breast Cancer Awareness Month, there are lots of events happening in our community to support this cause. Our friends and partners at the Breast Cancer Research Foundation of Alabama have a tremendous number of events happening in October, from motorcycle rides to shopping nights to a restaurant week to pink ribbon bagels. I encourage you to visit their website or the Cancer Center's for a listing of all the great community events that you can become a part of!

We must remember that awareness for ALL cancers is a year-round activity, and the support of our community is critical in helping us achieve our mission of eliminating cancer as a public health problem. On behalf of the UAB Comprehensive Cancer Center, I thank you for your support.

-Ed Partridge, M.D.

Thursday, January 27, 2011

The Message from the Recent FDA Ruling: Don't Panic

This week the FDA announced that it has found a possible link between breast implants and a very rare type of cancer. According to the report, the agency documented about 60 cases of anaplastic large cell lymphoma among the five to 10 million women with implants. Based on these findings, the FDA is requiring changes to the product's labeling.

Breast implants have been scrutinized for decades, and it is the FDA's responsibility to inspect such products for public safety. However, the takeaway message from this study for women with breast implants is this: Don't panic!

To put this study in perspective: If 60 cases occurred among six million implants, that comes to a lifetime risk of one in 100,000 for this type of cancer. However, the average woman has a one in 17 lifetime risk of developing colorectal cancer, regardless of whether she has implants or not.

I urge all women to monitor their breast health through self-exams and regular mammograms. For those with implants, check for any irregularities such as fluid collection around the implant, pain or breast asymmetry. The risk of developing cancer is extremely low, and these results are very early. However, I encourage women to contact their healthcare professional if they have any concerns or further questions. Keeping a watchful eye on your health is good practice, no matter what.

-Ed Partridge, M.D.

Thursday, January 6, 2011

A Survivor's Inspiring Story

Dianne Poe with six of her seven grandchildren.
Tonight I had the opportunity to meet Dianne Poe, a breast cancer survivor who was treated at the UAB Comprehensive Cancer Center. Dianne was diagnosed with breast cancer in 2006, and ended up traveling from her hometown of Lanett, Alabama, to UAB for her treatment. Tonight, she shared her cancer journey at the Cancer Center’s annual Progress & Promise event.

As I listened to Diane tell her story, I was struck by what a courageous and inspiring person she is. Throughout her experience, she maintained a strong, positive attitude, which can be difficult to do when facing a disease such as cancer. And not only is Dianne a warm and gracious person, she’s also a perfect example of the translational research that we do here at the Cancer Center.

When Dianne came to the Cancer Center, she enrolled in a clinical trial that was born out of basic science research conducted right here in our laboratories. She was one of the first patients to enroll in this trial, and in just over a year, she was cancer-free. This is what we refer to as “translational research” – that process of taking scientific findings from the laboratory and translating them into therapies or treatments for patients in the clinic. Our ability to conduct groundbreaking and innovative translational research is one of the many things that sets the UAB Comprehensive Cancer Center apart.

I’m so honored to have had the opportunity to meet and get to know Dianne tonight, and I thank her for sharing her story with me. She, along with all of our patients, is a reminder of what we at the UAB Comprehensive Cancer Center are working toward every day – a world where cancer is no longer a major public health problem.

-Ed Partridge, M.D.

Friday, December 17, 2010

Avastin and Breast Cancer - Guest Blog by Dr. Andres Forero

Andres Forero-Torres, M.D.
Yesterday, the Food and Drug Administration (FDA) recommended that the drug Avastin not be used to treat breast cancer. This is causing quite a bit of discussion in the cancer community and media, as this ruling affects thousands of breast cancer patients. 

The FDA says clinical trials have shown that Avastin does not prolong survival for patients with metastatic breast cancer. However, other studies have shown that the combination of Avastin and Taxol does improve disease-free survival.  The FDA recommendation also does not apply to clinical trials of Avastin used in combination with hormonal treatments or for clinical trials for the prevention of breast cancer. However, the European Committee for Medicinal Products for Human Use (CHMP) is keeping the approval of Avastin in combination with Taxol for metastatic breast cancer.

Patients taking Avastin should continue taking the drug and talk with their physician. Patients enrolled in clinical trials using Avastin, including those here at the UAB Comprehensive Cancer Center, should continue taking the drug until advised differently by study managers.

Andres Forero-Torres, M.D., is a hematologist-oncologist and senior scientist at the UAB Comprehensive Cancer Center. He specializes in the research and treatment of breast cancer and lymphomas.