What is Leukemia?
Leukemia is a type of cancer that starts in blood-forming tissue such as the bone marrow and causes large numbers of blood cells to be produced and enter the bloodstream. There are an estimated 52,380 new cases of leukemia in the United States in 2014. There are an estimated 24,090 deaths due to Leukemia predicted this year.
What is Lymphoma?
Lymphomas are cancers that affect the cells in the immune system and are the most common type of blood cancer. Depending on the specific cells that are affected, each case is classified as one of two primary types – Hodgkin’s or non-Hodgkin’s – and these two categories break down further into five types of Hodgkin’s lymphoma and more than 40 subtypes of non-Hodgkin’s.
Of the two types, non-Hodgkin’s lymphoma is far more common, affecting approximately 70,800 estimated in 2014 in the United States, as opposed to 9,190 cases of Hodgkin’s lymphoma.
Non-Hodgkin's lymphoma is any of a large group of cancers of lymphocytes (white blood cells). Non-Hodgkin's lymphomas can occur at any age and are often marked by lymph nodes that are larger than normal, fever, and weight loss.
Hodgkin's lymphoma is a cancer of the immune system that is marked by the presence of a type of cell called the Reed-Sternberg cell. Symptoms include the painless enlargement of lymph nodes, spleen, or other immune tissue. Other symptoms include fever, weight loss, fatigue, or night sweats. Also called Hodgkin disease.
The UAB Comprehensive Cancer Center is a nationally recognized leader in the field of leukemia and lymphoma research and actively conducts clinical trials for both acute and chronic leukemia patients and both Hodgkin’s and non-Hodgkin’s lymphoma patients.
The Cancer Center has been involved in several clinical trials of Clofarabine, an anti-leukemia drug developed here in Birmingham. Many of these examine the drug’s effects on patients older than 60.
The Cancer Center has also been involved in several clinical trials and conducts much epidemiologic study on the outcomes of minority patients with lymphoma.
Much leukemia and lymphoma research is done through UAB’s Bone Marrow Transplant Unit, which is one of the 10 largest in the country.
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